What are the Histological Features of Neural Tube Defects?
Histologically, NTDs are characterized by disrupted architecture of the central nervous system tissues:
- [Anencephaly](#): Histological examination reveals absence of cerebral hemispheres and presence of disorganized neural tissue. - [Spina Bifida](#): The spinal cord and meninges may herniate out of the vertebral column, resulting in exposure to amniotic fluid, which can cause further damage. - [Encephalocele](#): Histology shows herniated brain tissue covered by membranes, often with gliosis and necrosis.
