What Techniques are Used for Genetic Profiling in Histology?
Several advanced techniques are employed for genetic profiling in histology: - Polymerase Chain Reaction (PCR): This technique amplifies small segments of DNA, making it easier to study specific genetic markers. - Next-Generation Sequencing (NGS): NGS allows for the comprehensive sequencing of entire genomes or targeted regions, providing high-resolution data on genetic variations. - Fluorescence In Situ Hybridization (FISH): FISH is used to detect and localize the presence or absence of specific DNA sequences on chromosomes. - Microarray Analysis: This method helps in examining the expression of thousands of genes simultaneously to identify gene activation patterns.