Nrf2 can be studied in histology through various techniques, including immunohistochemistry (IHC), which allows for the visualization of Nrf2 expression and localization within tissue sections. Additionally, Western blotting and quantitative PCR (qPCR) can be used to measure Nrf2 levels and its target genes at the protein and mRNA levels, respectively. These methods provide insights into the functional status of Nrf2 in different tissues.