How is Tumor Aggressiveness Assessed Histologically?
Histological assessment of tumor aggressiveness typically involves examining tissue samples under a microscope. Key indicators include:
Cellular differentiation: Poorly differentiated cells often indicate a more aggressive tumor. Mitotic activity: Increased numbers of mitotic figures suggest rapid cell division and higher aggressiveness. Necrosis: Areas of necrosis within the tumor can be a sign of rapid growth outpacing the blood supply. Invasion: The presence of tumor cells invading surrounding tissues or vessels is a hallmark of aggressive behavior.
