How is Mitochondrial Dysfunction Studied in Histology?
Histological studies of mitochondrial dysfunction often involve advanced imaging techniques and biochemical assays. Electron microscopy provides high-resolution images of mitochondrial ultrastructure, revealing morphological abnormalities. Immunohistochemistry can be used to detect specific mitochondrial proteins and assess their localization and expression levels. Additionally, assays measuring enzyme activity, such as COX and SDH, provide functional insights into mitochondrial health.
