How Does Mitochondrial Dysfunction Affect Cellular Function?
Mitochondrial dysfunction can have widespread effects on cellular function. Cells may experience energy deficits due to reduced ATP production, leading to impaired cellular processes. The accumulation of ROS can cause oxidative damage to proteins, lipids, and DNA, further compromising cellular integrity. Additionally, dysfunctional mitochondria can trigger apoptotic pathways, leading to programmed cell death.