How is Microglial Proliferation Studied in Histology?
In histology, microglial proliferation is often studied using various techniques: - Immunohistochemistry: This technique involves using antibodies to detect specific markers such as Iba1 and Ki67 to visualize microglia and their proliferative state. - BrdU Incorporation: Bromodeoxyuridine (BrdU) is a thymidine analog that gets incorporated into DNA during cell division, allowing for the identification of proliferating cells. - Flow Cytometry: This technique can be used to analyze cell populations and identify proliferating microglia based on specific markers.
