The adjustment process may vary depending on the type of holder being used, but generally, it involves the following steps:
Placement: Carefully place the tissue block into the holder, ensuring it is correctly oriented. Securing: Tighten any screws or clamps to secure the sample firmly in place. Alignment: Align the holder under the microtome blade to ensure even and precise sectioning. Adjustment: Make fine adjustments to the holder to eliminate any wobbling or misalignment.
