What is the Significance of Microglial Proliferation in Disease?
Microglial proliferation has both beneficial and detrimental effects depending on the context: - Protective Role: In acute injuries and infections, microglial proliferation helps in clearing debris and pathogens, contributing to tissue repair and recovery. - Pathological Role: In chronic neuroinflammation, excessive or uncontrolled microglial proliferation can lead to the release of neurotoxic substances, exacerbating conditions such as Alzheimer's disease and multiple sclerosis.
