How is Herpes Simplex Diagnosed Through Histology?
The diagnosis of herpes simplex can be confirmed through histological examination of tissue samples. A Tzanck smear is a common test where cells from the base of a vesicle are scraped and stained. The presence of multinucleated giant cells and inclusion bodies can be indicative of an HSV infection. Additionally, immunohistochemistry can be used to detect viral antigens in tissue samples, providing further confirmation.
