Detection of FAP in histological samples is typically carried out using immunohistochemical staining. Specific antibodies against FAP are used to stain tissue sections, which are then examined under a microscope. Positive staining indicates the presence of FAP, which is often localized to the stromal fibroblasts in the tissue. This technique helps in the identification of FAP-expressing cells and provides insights into the extent of tissue remodeling or tumor-stroma interactions.
