What are the Therapeutic Implications of Targeting FAP?
Targeting FAP presents a promising therapeutic strategy, especially in oncology. FAP inhibitors, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to selectively target FAP-expressing cells. By disrupting the pro-tumorigenic functions of FAP, these therapies aim to hinder tumor growth and metastasis, and potentially enhance the efficacy of existing treatments.