What Are the Histological Grades of Breast Cancer?
Breast cancers are graded based on their histological appearance. The most commonly used system is the Nottingham Grading System, which evaluates:
Tubule Formation: The degree to which the tumor cells form glandular structures. Nuclear Pleomorphism: Variation in the size and shape of the cell nuclei. Mitotic Count: The number of cells undergoing mitosis.
Each feature is scored, and the total score determines the grade: Grade 1 (low grade), Grade 2 (intermediate grade), or Grade 3 (high grade). Higher grades are associated with a poorer prognosis.
