How Does the Cellular Environment Influence Neuronal Survival?
The cellular environment is critical for neuronal survival. Glial cells, including astrocytes and microglia, provide support and protection to neurons. Astrocytes regulate the extracellular environment, maintain ion balance, and supply metabolic substrates. Microglia act as immune cells in the brain, responding to injury and infection. The extracellular matrix (ECM) provides structural support and contains molecules that facilitate cell signaling and adhesion.
