How Do Environmental Stressors Affect Neuronal Survival?
Environmental stressors such as oxidative stress and inflammation can significantly impact neuronal survival. Oxidative stress results from the accumulation of reactive oxygen species (ROS), which can damage cellular components, including DNA, proteins, and lipids. Chronic inflammation can lead to the release of pro-inflammatory cytokines that exacerbate neuronal damage. Hypoxia, or reduced oxygen supply, can also induce neuronal death by disrupting cellular metabolism and energy production.