How Does Label-Free Detection Compare to Traditional Staining?
Traditional staining methods, such as H&E and immunohistochemistry, have been the gold standard in histology for many years. These methods are well-established and provide clear and specific information about tissue morphology and specific proteins. However, they have several drawbacks, including potential artifacts, the need for multiple steps and reagents, and the inability to be used for live-cell imaging.
In contrast, label-free detection provides a more natural view of the tissue, is faster and cheaper, and can be used for live imaging. However, it often requires more advanced technology and expertise.
