What are the Implications of Senescent Cells in Therapeutics?
Understanding the biology of senescent cells has significant therapeutic implications. Strategies to target senescent cells include senolytics, which are drugs that selectively induce death of senescent cells, and senomorphics, which modulate the SASP to reduce its detrimental effects. Therapies targeting senescent cells hold promise in treating age-related diseases, improving healthspan, and potentially extending lifespan.