How Does Histology Help in Diagnosing Musculoskeletal Disorders?
Histological examination involves the analysis of tissue samples obtained through biopsy or surgery. By examining these samples under a microscope, histologists can identify abnormalities in the structure and organization of cells and extracellular matrix. For instance, in conditions like osteoarthritis, histological analysis reveals the degradation of articular cartilage and changes in subchondral bone. Similarly, in muscular dystrophies, one can observe the replacement of muscle fibers with fatty and fibrous tissue.