Can Histology Differentiate Between Types of Muscular Dystrophy?
Yes, histological analysis can differentiate between various types of muscular dystrophy. For example:
Duchenne Muscular Dystrophy: Shows complete absence of dystrophin protein, muscle fiber necrosis, and replacement by fatty and fibrous tissue. Becker Muscular Dystrophy: Partial deficiency of dystrophin with a similar but less severe histological appearance compared to Duchenne. Myotonic Dystrophy: Presence of ring fibers, central nuclei, and atrophy of type I muscle fibers.
