How Does Epigenetic Heterogeneity Affect Cellular Function?

Epigenetic heterogeneity can significantly impact cellular function by altering gene expression profiles. For example, in a tissue sample, different cells might exhibit varying levels of DNA methylation or histone acetylation, leading to differences in gene activity. This variability can affect cell differentiation, proliferation, and response to environmental stimuli. It is particularly relevant in the context of cancer, where epigenetic alterations can contribute to tumor heterogeneity, affecting disease progression and treatment response.