The impact of ATP loss on tissues and organs depends on the extent and duration of the deficiency:
1. Muscle Tissue: ATP depletion can cause muscle fatigue, weakness, and even rhabdomyolysis in severe cases. 2. Nervous Tissue: Neurons are highly dependent on ATP. Its loss can lead to impaired synaptic transmission, neuronal injury, and neurodegenerative conditions. 3. Cardiac Tissue: The heart requires constant ATP for contraction. ATP loss can result in impaired cardiac function, arrhythmias, and heart failure.
