How do Thromboxanes Affect Vascular Smooth Muscle?
Thromboxanes also play a significant role in the modulation of vascular smooth muscle. TXA2 induces vasoconstriction, which helps to reduce blood flow to the site of injury and limit blood loss. This vasoconstrictive effect is mediated through receptors on the smooth muscle cells, leading to an increase in intracellular calcium levels and subsequent muscle contraction.
