What Histological Changes are Seen in Peptic Ulcers?
Peptic ulcers are open sores that develop on the inner lining of the stomach or the upper part of the small intestine. Histologically, a peptic ulcer exhibits a loss of the surface epithelium, with a necrotic debris layer overlying the ulcer base. Beneath this layer, there is a zone of acute inflammation with numerous neutrophils, followed by granulation tissue and fibrosis as the ulcer heals.
