How Do Signaling Pathways Contribute to Growth Inhibition?
Various signaling pathways are involved in growth inhibition. One of the most well-known pathways is the p53 pathway. The p53 protein acts as a tumor suppressor by inducing cell cycle arrest, apoptosis, or senescence in response to cellular stress. Another important pathway is the TGF-beta pathway, which regulates cell growth, differentiation, and apoptosis. Dysregulation of these pathways can lead to uncontrolled cell proliferation and cancer.
