How Does Growth Inhibition Impact Cancer Development?
Growth inhibition is a critical mechanism for preventing cancer development. In normal tissues, growth-inhibitory signals ensure that cells do not proliferate uncontrollably. However, in cancer, these mechanisms are often disrupted. Mutations in genes encoding proteins involved in growth inhibition, such as p53 and Rb, can lead to the loss of cell cycle control and tumor formation. Consequently, understanding the molecular basis of growth inhibition is essential for developing effective cancer therapies.
