mutations

How Do Mutations Affect Histological Structures?

Mutations can have a wide range of effects on tissues and cells:
Cellular Morphology: Mutations might alter cell shape, size, and organization. This is often observed in cancerous tissues where cells lose their normal architecture.
Tissue Function: A mutation in a gene responsible for a crucial protein may lead to loss of function, impacting tissue health. For example, mutations in the CFTR gene cause cystic fibrosis, affecting the respiratory and digestive systems.
Cell Proliferation: Mutations in genes controlling cell division can lead to uncontrolled proliferation, a hallmark of cancer.
Apoptosis: Mutations in apoptotic genes can prevent programmed cell death, allowing damaged cells to survive and potentially become cancerous.

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