How Do Molecular Markers Influence Tumor Aggressiveness?
In addition to histological features, molecular markers can provide valuable insights into a tumor's aggressiveness. For example, overexpression of HER2/neu in breast cancer or mutations in genes such as KRAS or BRAF in colorectal cancer are associated with more aggressive behavior. Immunohistochemistry (IHC) and other molecular techniques are often used to detect these markers within tissue samples.
