How are Bleeding Disorders Diagnosed Histologically?
The diagnosis of bleeding disorders through histology involves several techniques:
Biopsy: A tissue biopsy can reveal structural abnormalities in blood vessels or tissues affected by bleeding. Blood Smears: Examining blood smears under a microscope can identify abnormal platelet shapes, sizes, and counts. Immunohistochemistry: This technique uses antibodies to detect specific clotting factors or platelet proteins in tissue samples. Electron Microscopy: Provides detailed images of platelets and vascular structures to identify ultrastructural defects.
