What is the Role of Grading Systems in Determining Tumor Aggressiveness?
Grading systems, such as the Gleason score for prostate cancer or the Nottingham grading system for breast cancer, are used to categorize tumors based on their histological features. These systems typically consider factors like glandular formation, nuclear pleomorphism, and mitotic count to assign a grade, which correlates with aggressiveness and prognosis. Higher grades generally indicate more aggressive tumors.
