How Do Histological Techniques Aid in the Study of Motility Disorders?
Various histological techniques are employed to study motility disorders:
- Histochemical Staining: Techniques like Hematoxylin and Eosin (H&E) staining help visualize general tissue architecture. - Immunohistochemistry: This technique uses antibodies to detect specific proteins, such as neuronal markers, to assess the integrity of the enteric nervous system. - Electron Microscopy: Provides detailed images of cellular structures, useful for examining the ultrastructure of smooth muscle cells and enteric neurons. - In Situ Hybridization: Detects specific nucleic acid sequences, helping to identify genetic mutations associated with congenital motility disorders.
