How Do Chronic Conditions Affect Tissue Remodeling?
In chronic conditions, tissue remodeling is a continuous process involving both destruction and repair. This is often mediated by fibroblasts, which produce collagen and other extracellular matrix components. Over time, this can lead to fibrosis, which can disrupt normal tissue architecture and function. Chronic inflammation may also stimulate the formation of new blood vessels, a process known as angiogenesis, to supply the inflamed tissue with nutrients and oxygen.