What Is the Role of Macrophages in Chronic Conditions?
Macrophages play a crucial role in chronic conditions. They are involved in both the perpetuation of inflammation and tissue repair. In chronic inflammation, macrophages can merge to form multinucleated giant cells, a feature often observed in granulomas. They secrete a variety of cytokines and growth factors that influence the behavior of other cells, contributing to both tissue damage and repair processes.
