What Are the Key Parameters in Histological Drug Studies?

Several parameters are critical when conducting histological drug studies:

1. Cellular Morphology: Changes in the shape, size, and structure of cells can indicate drug efficacy or toxicity.
2. Tissue Architecture: Observing the organization and integrity of tissues helps determine the overall impact of the drug.
3. Protein Expression: Using immunohistochemistry, histologists can measure alterations in protein levels that may correlate with drug action.
4. Gene Expression: In situ hybridization can reveal changes in gene expression patterns, offering insights into the drug's molecular mechanisms.