How Is Chronic Inflammation Identified Histologically?
Chronic inflammation is characterized by the presence of certain key cellular and tissue features. These include an abundance of lymphocytes, macrophages, and plasma cells. Fibrosis, or the excessive deposition of extracellular matrix, particularly collagen, is another hallmark. The formation of granulomas, which are organized clusters of macrophages often surrounded by lymphocytes, may also be seen in specific chronic inflammatory conditions such as tuberculosis.
