Several approaches can be taken to improve the efficiency of adsorption in histological staining: - Use of Mordants: Mordants are substances that enhance the binding of stains to tissues. For example, aluminum salts are often used with hematoxylin to improve nuclear staining. - Optimizing Conditions: Careful adjustment of pH, temperature, and concentration can significantly improve the efficiency of adsorption. - Multiple Staining: Sometimes, a combination of stains is used to achieve better differentiation of tissue components.
