Potential strategies to prevent or mitigate calcium overload include:
1. Calcium Channel Blockers: Drugs that inhibit calcium entry through voltage-gated calcium channels. 2. Antioxidants: Compounds that reduce oxidative stress and protect against calcium-induced damage. 3. Mitochondrial Protectants: Agents that prevent the opening of the mPTP and preserve mitochondrial function. 4. Gene Therapy: Targeting genes involved in calcium regulation to correct underlying defects.
