How does Histology Relate to Pulmonary Function Tests?
Histology provides a microscopic view of lung tissues, which helps to explain the structural abnormalities that may be responsible for impaired lung function observed in PFTs. For instance, in diseases like COPD, histological examination might reveal the destruction of alveolar walls and loss of elastic fibers, which correlate with reduced lung elasticity and airflow obstruction seen in spirometry.