In histology, M2 macrophages can be identified using specific markers. Commonly used markers for M2 macrophages include CD163, CD206 (mannose receptor), and arginase-1. Immunohistochemistry (IHC) and immunofluorescence techniques are typically employed to detect these markers in tissue samples. Staining with these markers allows for the differentiation of M2 macrophages from other cell types and macrophage subsets.
