How are Inflammatory Myopathies Identified Histologically?
Inflammatory myopathies include conditions like polymyositis, dermatomyositis, and inclusion body myositis. Histologically, they are identified by:
- Inflammatory Infiltrates: Presence of lymphocytes, macrophages, and plasma cells. - Muscle Fiber Necrosis and Phagocytosis: Damaged fibers being engulfed by macrophages. - Perifascicular Atrophy: In dermatomyositis, atrophy of muscle fibers around the periphery of muscle fascicles.
