How Does the Extracellular Matrix Influence Cells?
The extracellular matrix (ECM) is a complex network of proteins and polysaccharides that provides structural support to cells. It influences cell behavior through biochemical and mechanical signals. ECM components like collagen, elastin, and fibronectin interact with cell surface receptors, such as integrins, to regulate processes like cell adhesion, migration, proliferation, and differentiation. Alterations in ECM composition can lead to diseases like fibrosis and cancer.