In histology, fibroblasts can be studied using various staining techniques. One common method is Hematoxylin and Eosin (H&E) staining, which highlights the cell nuclei and cytoplasm. Immunohistochemistry can also be used to detect specific proteins expressed by fibroblasts, such as vimentin, a marker for mesenchymal cells. Electron microscopy provides detailed images of the fibroblast's ultrastructure.