The biosynthesis of glycerolipids is tightly regulated by various mechanisms: - Enzyme Regulation: The activity of GPAT, LPAAT, and DGAT is controlled by hormonal signals and metabolic states. - Feedback Inhibition: High levels of end products like TAG can inhibit the enzymatic steps upstream in the pathway. - Transcriptional Regulation: The expression of genes encoding for the biosynthetic enzymes can be upregulated or downregulated depending on the cell’s needs.
