How Are Adverse Drug Reactions Studied Histologically?
Adverse drug reactions (ADRs) can lead to significant tissue damage, which can be studied through histological techniques. For instance, liver toxicity induced by certain medications can be identified by histopathological changes such as hepatocyte necrosis or fibrosis. Similarly, kidney toxicity can be examined by assessing glomerular and tubular damage. Identifying these ADRs early through histological analysis can prompt modifications in drug formulation or usage.