Can Postsynaptic Densities be Targeted for Therapeutic Interventions?
Given their central role in synaptic function and plasticity, PSDs are potential targets for therapeutic interventions in neurological disorders. Modulating the activity of specific proteins within PSDs, such as NMDA receptors or scaffolding proteins, could help restore normal synaptic function and alleviate symptoms associated with these disorders. Ongoing research aims to identify and develop such targeted therapies.
