What is the Composition of Postsynaptic Densities?
The composition of PSDs includes a complex array of proteins. Key components include glutamate receptors such as AMPA and NMDA receptors, scaffolding proteins like PSD-95 and Shank, cytoskeletal proteins, and signaling molecules like kinases and phosphatases. This intricate assembly of proteins allows for the precise regulation of synaptic activity and plasticity.