What are Some Pathological Conditions Associated with Dysfunctional Postsynaptic Densities?
Dysfunctional PSDs are implicated in various neurological disorders. For instance, abnormalities in PSD components have been linked to autism spectrum disorders, schizophrenia, and Alzheimer's disease. Disruptions in the organization and function of PSDs can lead to impaired synaptic transmission and plasticity, contributing to the pathogenesis of these conditions.