tumor cell death

What Are the Main Types of Tumor Cell Death?

The primary types of tumor cell death include apoptosis, necrosis, and autophagy.
- Apoptosis: Also known as programmed cell death, apoptosis is a highly regulated process that involves cell shrinkage, DNA fragmentation, and membrane blebbing. Caspases, a family of proteases, play a crucial role in executing apoptosis.
- Necrosis: In contrast to apoptosis, necrosis is an uncontrolled form of cell death resulting from acute damage. It is characterized by cell swelling, loss of membrane integrity, and inflammation.
- Autophagy: This is a survival mechanism where cells degrade and recycle their own components. However, excessive autophagy can lead to cell death, termed autophagic cell death.

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