Can histological examinations help diagnose predisposition to infections?
Yes, histological examinations can provide valuable insights into predisposition to infections. Tissue biopsies can reveal structural abnormalities, such as epithelial damage or fibrosis, that compromise barrier function. Immunohistochemistry can be used to assess the presence and activity of immune cells within tissues, identifying deficiencies or dysregulations. Additionally, histological staining techniques can detect the presence of pathogens or their effects on tissue architecture, aiding in the diagnosis of underlying conditions that predispose individuals to infections.
