What histological features are indicative of immune system dysregulation?
Histological features indicative of immune system dysregulation include lymphoid hyperplasia, indicating excessive immune cell proliferation, and lymphoid depletion, signifying reduced immune cell presence. The presence of abnormal immune cell infiltrates, such as eosinophils or neutrophils, can suggest underlying conditions like allergies or autoimmune diseases. Additionally, tissue necrosis and apoptosis can indicate excessive immune responses leading to tissue damage. Identifying these features through histological analysis can help diagnose and manage immune-related disorders.
