Are There Any Limitations to Warthin-Starry Stain?
Despite its advantages, the Warthin-Starry stain has some limitations. The technique is technically challenging and requires meticulous preparation to avoid artifacts. Additionally, the stain is not specific to any particular organism, meaning that it can detect various types of bacteria, potentially leading to false positives. Therefore, it is often used in conjunction with other diagnostic methods, such as PCR or immunohistochemistry, to confirm the presence of specific pathogens.
